The Sempermed Semperguard disposable general purpose & examination glove is made of nitrile rubber, is packaged 10 boxes per case, comes in blue and meets 21 CFR Part 177 standards. R.S. Hughes sells a large variety of gloves designed and constructed with many different types of materials to meet different applications. This particular glove is made with Nitrile Rubber, offers a beaded cuff, with a rough finish and are powder free. Proper sizing is important when buying this item. The size for this product is large.