The Sempermed Semperguard disposable general purpose glove is made of nitrile rubber, is packaged 10 boxes per case, comes in blue and meets 21 CFR Part 177 standards. R.S. Hughes sells a large variety of gloves designed and constructed with many different types of materials to meet different applications. This particular glove is made with Nitrile Rubber, offers a beaded cuff, with a rough finish and are powder free. Proper sizing is important when buying this item. The size for this product is large.